Another 71 cases of monkeypox have been identified in England over the weekend bringing the UK total to 179, the UK Health Security Agency (UKHSA) says.
New guidance is advising anyone with the virus to abstain from sex while they have symptoms.
They are also told to use condoms for eight weeks after an infection as a precaution.
New guidance for doctors and other healthcare workers to help control the latest outbreak has now been agreed by the four health authorities in England, Wales, Scotland and Northern Ireland.
People who have tested positive for the virus and their close contacts are being told to isolate at home for 21 days.
They should avoid contact with other people until all lesions – or blisters – have healed and scabs have dried off.
Anyone with a confirmed infection is now being advised to abstain from sex while they have symptoms.
The guidance says that while there is currently no available evidence that monkeypox can be spread in sexual fluids, people confirmed to have the virus are advised to use condoms for eight weeks after infection as a precaution.